OPIUM POPPY (Papaver somniferum). Family: Papaveraceae
The opium poppy occurs as a garden escapee and is a relict of earlier cultivation; it has been recorded throughout the British Isles (for distribution map for see: National Biodiversity Database). You can find it growing profusely as a garden weed and on disturbed soils on wasteland and waysides and in the upper zones of coastal shingle. Almost all our self-sown plants (and those commonly grown as garden ornamentals) belong to the subspecies hortense.
Opium poppy from Köhler’sMedizinal Pflanzen , vol. 1 (1887)
Opium poppy was first domesticated in the Neolithic period (at c. 5000 BC) in the western Mediterranean, which is the natural habitat of the wild progenitor Papaver somniferum subsp. segiterum (Bakels 1982; Simmonds 1976: 318; Zohary et al. 2012: 109-111, map 14). It was, therefore, not one of the founder crops of early farming that originated in southwest Asia, but instead complemented the Neolithic crop package at a later date and then rapidly spread throughout Europe (Bakels 2014; Salavert et al. 2018). Two series of cultivars have evolved from Papaver somniferum: subsp. hortense and subsp. somniferum, and both are derived from the wild Papaver somniferum subsp. segiterum (Simmonds 1978: 318; Zohary et al. 2012: 109). The oil poppy varieties—with edible seeds—are of the subsp. hortense, and the opium cultivars—used for the narcotic properties of the latex—belong to the subsp. somniferum.
Opium poppies are characterised by their robust build, their large, hairless, glaucous leaves and their large capsules and flowers, which range from white, through a spectrum of pinks and mauves, to deep purple. Our local forms of subsp. hortense differ from subsp. somniferum in having black seeds and dehiscent capsules (i.e., with pores that allow the seeds to be shed; subsp. somniferum has white or yellow seeds and indehiscent capsules).
Opium harvesting and its therapeutic uses
The opium is harvested by making incisions in the green seed capsules as soon as the petals have dropped. The latex that oozes from the incisions is allowed to congeal to form a gum (the opium) and is then peeled off. The therapeutic properties of opium are due to the high proportions of alkaloids[i]. There are a total of 40 alkaloids in opium poppy, the most important of which are: morphine, codeine, thebaine, papaverine and noscopine (Dittbrenner et al. 2009). Morphine is present in the highest concentration and the other four dominant alkaloids have been shown to occur in varying proportions dependent on different factors, possibly including the growth conditions during the developmental stages of the opium poppy plants (ibid.: 105-106). Morphine and codeine are well known for their analgesic properties, thebaine is a stimulant (however, as Dittbrenner et al. note, it is most commonly manufactured into other pain killers, rather than being used directly for its restorative effects), papaverine is an antispasmodic or muscle relaxant, and noscopine is used for its antitussive (cough-suppressing) properties (Dittbrenner et al. 209: 103: see also: KewGardens - a tale of two poppies).
Opium
poppy seeds as food
Because they have dehiscent capsules the seeds of our local opium poppies can be gathered in much the same way as those of our common or field poppies (Papaver rhoeas), and they are just as oil-rich and flavoursome (see: NutritionValue.org; Duke 1973: table 1). They can be eaten either raw or cooked, can be ground and made into porridge, and used in cakes and pastries as flavourings or decoration (Duke 1973: 390).
Opium poppy seeds contain minute amounts of alkaloids in comparison with the proportions present in the latex (Plants for a Future database). However, a tea made from poppy seeds, if taken over prolonged periods, has been found to cause users to become dependent on opium such that they are required to detoxify in order to reverse their addictions (Haber et al. 2019: see also: US Drug Enforcement Administration - Drug & Chemical Evaluation Section 2019).
Opium poppy leaves are acutely bitter and inedible.
Ethnographic
accounts of the medicinal uses of opium poppies
There are numerous reports in the ethnographic literature about the therapeutic uses of Papaver somniferum (e.g., see Duke 1973). Those relating to the efficacious properties of the main constituent alkaloids (as described above) are the most common and, unsurprisingly, the use of opium poppies for pain relief is frequently referred to in traditional medicine. In the Basilicata region of southern Italy knowledge of plant-based remedies was obtained during interviews with one of the last surviving healers known as ‘Zi Matteo’ (Uncle Mathew; Montesano et al. 2012). The 87 year old, together with ten interviewees chosen from amongst the older inhabitants in his local town, reported the uses of 52 plants, including a decoction of the fruits of opium poppies—to be taken orally—which was prescribed as a tranquillizer (ibid.: table 1). In western Gironès, Catalonia, the flowers, fruits and seeds prepared in a mouthwash or an infusion are used as an analgesic or sedative (Gras et al. 2019: table 2). According to archival records dating to the 1930s that were collated by the Polish ethnographer Adam Fischer (1889-1943), in areas of the Polish-Lithuanian-Belarusian borderland painful toothache was treated with Papaver somniferum (plant parts not specified; Kujawska et al. 2017: table 3). Opium poppy is just one of 153 plant taxa (with 290 uses) that was reported at the time of Fischer’s survey.
In rural areas of the Upper Guadiana River area in Castile-La Mancha (central Spain) in addition to being administered for pain relief (e.g., for toothache) opium poppies are recorded as being used to treat a range of other common ailments (Rivera et al. 2019: table 5). For example, the flowers and fruits—prepared as infusions or decoctions and taken orally—are given to alleviate insomnia and nervousness/anxiety, and an infusion of the fruits is applied externally (e.g., to toes and fingers) to treat cellulitis and paronychia (infections of the skin and nails, respectively). Papaver somniferum (prepared as a decoction to be drunk) is one of 17 plant species recorded as being used in 19th and 20th century traditional medicine in Italy (specifically Fruili-Venezia Giulia, northeast Italy) to treat epilepsy (Tagarelli et al. 2013: 610). In Kırklareli Province in northwest Turkey dried opium latex is taken orally to treat coughs (Kültür 2007: table 1). And between the 1860s and 1970s in Romania opium poppies (either the whole plant or just the seeds, and prepared in a tea to be drunk or used externally in a bath) were prescribed for children to alleviate symptoms of coughs, colic, stomach pain, measles and insomnia (Petran et al. 2020: table 3).
In the Fenlands of Cambridgeshire and Lincolnshire in the early 19th century ‘poppy tea’ was considered to be an effective treatment for ‘ague’[ii] and rheumatism (Allen and Hatfield 2004: 77). The white-flowered form of Papaver somniferum was commonly grown in cottage gardens thus providing a plentiful source of opium and, as the authors comment, with the consequences that: “for several months of the year the Fenland people were largely drugged with opium, a fact to which their stunted physique was commonly attributed” (for more accounts of opium taking in the Fens see: All Things Georgian – Opium Eating: theLincolnshire Fens in the early nineteenth century).
Ethnobotanical
accounts of preparing and consuming opium poppies
We are accustomed to seeing poppy seeds on bread rolls and in cakes in our local bakeries and there are many records of traditional recipes in which they are also ingredients and garnishes for pastries and confectioneries. For example in Belarus, according to the recollections of respondents to an ethnobotanical questionnaire carried out in 1883 by the Polish botanist Professor Józef Rostafiński, Papaver somniferum seeds were commonly used in breads and sweets (Łuczaj et al. 2013: table 3). And as a means of maintaining their cultural identities and traditions Moroccan migrants living in northwest Italy prepare foods and medicines using wild plants (e.g., including opium poppy seeds in baked goods) that they were familiar with and were common in their country of origin (Fontefrancesco et al. 2019: table 2).
In the Polish-Lithuanian-Belarusian borderland opium poppy seeds are ingredients in ‘kucja’, a special dish prepared on Christmas Eve (Kujawska et al. 2017: table 3); the recipe for ‘kucja’ (/‘kutia’ or ‘kuczija’) is as follows:
“Made of roasted pęczak (pearled barley) to which a mixture of mead and water is added, kutia is one of the most popular dishes in Eastern Poland. Sometimes raisins, nuts and poppy seed are also added. In Białystok, it is known as kucja, east of Warsaw it is on occasion called kuczija. In Kresy and Ukraine where kutia is also a Christmas Eve dish, it is believed that indispensable ingredients include “a bit of eternity and the happiness of the saints in heaven”. The ingredient of kutia that represents eternity is wheat, which is reborn every year, and the carefree life of saints is represented by honey.” (see also: Polish traditional Christmas eve dishes).
Much like our autumn harvest festivals during which produce from the land is offered in thanks during religious ceremonies, in rural Poland wreaths of plants are blessed in churches at certain times of the year to coincide with significant events in the agricultural seasonal cycle so as to guarantee the welfare and productivity of farms (Łuczaj 2011). Papaver somniferum is listed as being included in Assumption Day bouquets at the end of the 19th century—a tradition that has continued up to the present day despite fact that cultivation of the plants was ruled to be illegal in Poland in 1985 (ibid.: table 1; 72). The author describes the Assumption Day blessings:
“On Assumption Day (Zielna, or "Mary of the Herbs'), the 15th of August, specially arranged bouquets were brought to the church for blessing. These bouquets usually comprised the largest number of plants, including medicinal plants, apotropaic plants, and a variety of crops plants, such as cereals.” (ibid.: 67)
Prehistoric
and historic uses
There are a great many references in the archaeological literature to finds of Papaver somniferum on sites of all periods (e.g., from the Neolithic to the Medieval and later periods; see Kroll 1995: 57; 1996: 184; 1997: 43; 1998: 39; 1999: 142; 2000: 46; 2001: 44; Merlin 2003; Schultz-Motel 1994: 40). Waterlogged seeds and other plant parts are particularly numerous on Neolithic lake villages (pile dwellings or ‘pfahlbauten’[iii]) in Switzerland, France and southern Germany. At these sites typically hundreds or thousands of individual remains of opium poppies are preserved due to the fact that household rubbish (including food debris) was ejected from houses and rapidly became incorporated in the lake sediments below, thus preventing aerobic decay of fragile plant tissues (Colledge and Conolly 2014). Some charred items are reported but they are far outnumbered by waterlogged remains (for lists of Neolithic lake villages with c. 200 or more waterlogged opium poppy seeds, etc., see endnote[iv]; also: the Cultural Evolution of Neolithic Europe. EUROEVOL dataset).
Because of systematic excavation and sampling at these lake villages it has been possible to plot distributions and densities of preserved plant remains within and around the houses and therefore locate areas where processing and preparation activities took place. For example, as at Bad Bachau-Torwiesen II in Germany (Herbig 2006), where thousands of waterlogged opium poppy seeds were found:
“[Papaver somniferum seeds] were scattered quite regularly over the whole site, but still some differences between houses and some distinct accumulations can be observed. Houses 1, 3 and 11 were rich in opium poppy seeds and in addition, each of the buildings 5, 10 and 12 contained at least one big concentration of poppy seeds. On the other hand, poppy was almost totally absent from houses 6 and 13 as well as from all small houses. In front of house 3 and in the adjacent street, there was a big accumulation that might provide evidence of poppy processing in this area. So it cannot be ruled out that in some of the houses there was cultivation and/or preparation of opium poppy while in others there was not, and that poppy was not used in every house.” (Maier and Harwath 2011: 355-356)
There is material culture evidence
for the use of Papaver somniferum in
the eastern Mediterranean during the Minoan period (c. 3000-1450 BC; Askitopoulou
et al. 2002). In Minoan Crete a group of lekythi
jars shaped like poppy seed capsules with vertical ridges that mimic the cuts
made to release the latex are thought to have contained opium to be used for therapeutic
and ritual purposes (ibid.: 3; figure
1[v]).
The Minoan goddess of poppies—a symbol of fertility, is yet another example of the early association with opium. She is represented in a Cretan figurine with poppy seed capsule shaped adornments on her headdress (ibid.: 5; figure 3; link to: Minoan Poppy Goddess: Permanent exhibition of the Heraklion Museum, Crete http://odysseus.culture.gr/h/4/eh430.jsp?obj_id=7910). The authors describe the terracotta goddess figurine, which was found in a Late Minoan III period cult house, as measuring 78 cm in height and “bear[ing] on its head three movable hairpins shaped as beautiful, well-slit poppy capsules, called “mekones”, the poppies of Papaver somniferum” (ibid.: 5). Several bronze brooch pins with crystal heads shaped like poppy seed capsules were found in a royal tomb at Mycenae[vi] in southern Greece (dated to c. 1600-1100 BC) and also provide evidence for the cultural significance of opium at this early date (ibid.: 8; figure 5).
A long-standing controversy surrounding Cypriot base-ring juglets (e.g. examples at The British Museum) relates to whether or not they were integral to the trade in opium during the Late Bronze Age (c. 1600–1300 BC) in the eastern Mediterranean (Merrillees 1962). The juglets are shaped like inverted poppy seed heads and hence by association it was suggested would have held liquid opium for transportation (similar to the lekythi jars described above). However, in the absence of textual evidence in support of this idea and with no positive tests for the detection of opium alkaloids in residues taken from the inside of the juglets, the original theory was subsequently debunked (Bunimovitz and Lederman 2016). In their study Bunimovitz and Lederman tested for and detected a range of aromatic oils and concluded these were likely to have been stored in the vessels. More recently Merrillees’ original idea has been revived because lipid analysis of well-preserved residue (described as being ‘a dark brown, thick, oily material’) in one of the base-ring juglets (the example illustrated in the BM website above) has proved to be successful in detecting the alkaloids papaverine and thebaine and therefore these results suggest that the vessels may in fact have contained opium oil (Smith et al. 2018).
Persuasive evidence for Papaver somniferum being present because of its curative properties was found in a Roman farmhouse situated in the Pompeian countryside (Ciaraldi 2000). The farmhouse—Villa Vesuvio, and its contents were buried beneath the debris (/tephra) from the volcanic eruption of Vesuvius in AD 79. Seven storage vats (‘dolia’) were discovered in the cellar of the farmhouse and at the base of each one there was an organic (waterlogged) deposit. The vats possibly contained liquids at the time of the eruption and drying out of the organic layers had subsequently been prevented because of the periodic elevation of the ground water levels in the river valley in which the farmhouse was located. Ciaraldi examined the organic layer in dolium 2, which was completely sealed by the tephra layer thus preventing any contamination; preservation of waterlogged the plant remains was excellent:
“The dolium was filled up to a depth of almost 30 cm. with Prunus persica L. (peach) stones and Juglans regia L. (walnut), in a proportion suggested by the excavator as being of 70% and 30% respectively” (ibid.: 91), and below which there was a thick organic layer from which a sample for study was taken: “The sample consisted of a yellow, foamy matrix very rich in plant, bone and insect remains. The beginning of mineralisation was evident in the sample by the observation of small yellow lumps of minerals.” (ibid.: 93)
The list of plant species identified in dolium 2 included many for which there is a long history of their use for therapeutic purposes such as comfrey (Symphytum officinale), hemp (Cannabis sativa) and opium poppy (ibid.: table 1; 93). Faunal remains were also found in the organic layer, for example, bones of frogs, lizards and toads and, on the basis of the overall composition of plant and animal assemblage, Ciaraldi proposed that it was likely used in the manufacture of medicines (ibid.: table 3). More specifically that the ingredients were similar to those used to make mithridatium[vii] and theriac[viii]—both of which are referred to by classical authors such as Pliny the Elder and Dioscorides as antidotes for poisons and snake venom (ibid.: 95-97; see below for more references to Pliny and Dioscorides). The presence in one of the rooms of a small cooker for brewing the potions adds support to the idea that Villa Vesuvio could have been where these two medicines that both would have included opium poppies were produced.
Mineralised opium poppy seeds were recovered from the Cardo V sewer at Roman Herculaneum, which was also buried during the eruption of Vesuvius in AD 79 (Rowan 2017: table 3). The sewer had no outflows and therefore acted as a cesspit that was full of human and household waste deposited by the inhabitants of nearby shops and houses and, as such, its contents represented the diets of lower/middle class Romans who lived in the premises of the Insula Orientalis II. Because Cardo V had been completely covered by the detritus from the volcanic eruption there was excellent preservation of the plant remains (by waterlogging, charring and mineralisation), fish bones, shellfish and eggshell found in the refuse and faecal deposits.
Latrines discovered in Überlingen at a site near Lake Constance also proved to be a rich source of well-preserved and diverse plant materials that have been used to interpret diet and local environment during the late 11th-13th century, at a time when the town was an important link on the trade network in southern Germany (Märkle 2005). Excavations carried out in 1996 in an area that appeared to be the backyards of houses, revealed nine latrines, and due to the closeness of the lake and the high water table aerobic decay of the fragile plant remains was prevented. Seven of the latrines found at the residential plots were sampled and along with species of cereals, green leafy vegetables, herbs, spices, fruits and nuts (mostly waterlogged macrofossils but also some charred and mineralised), 88 opium poppy seeds (all waterlogged except for four specimens) were found in six latrines (Märkle 2005: table 3).
Opium poppies were identified in 14th and 15th century contexts in excavations at several localities in medieval Gdańsk in Poland (Badura et al. 2015: table 2). The types of economic plants identified in the archaeobotanical samples were compared with records in historical documents describing which provisions and traded goods were present in the city during the Medieval period. Of relevance here are the ‘Administrative and accounting documents of the Teutonic Order’ in which inventories were kept of food supplies (including plant species) stored in Gdańsk Castle kitchens and basements, and in the Great Mill[ix]; in the 1384 inventory Papaver somniferum is noted as being stored in the castle (ibid.: 443, 448).
From M. Lobel (1591)
Plantarum seu stirpium icones
Large numbers of poppy seeds were found in 15th century and 16th century cesspits (e.g., 3,053 seeds at Weender Straße 61 and 1,343 seeds at Johannisstraße 28) during the 1985/86 excavations that took place in Göttingen (Lower Saxony, Germany; Hellwig 1997: table 2). Flooding was common in the Late and Post-Medieval periods when tributaries of the river Leine traversed the city and therefore there was excellent preservation by waterlogging of the contents of the cesspits. Göttingen was a member of the Hanseatic League trading organisation from the mid 14th to late 16th centuries and throughout this period it was an important destination on trade routes in northern Europe. Consequently, in addition to plants found growing locally (including the opium poppies) there was evidence in the cesspits of imported, exotic species of cereals, fruits and spices, for example, rice (Oryza sativa), figs (Ficus carica), Melegueta pepper (Aframomum melegueta), black pepper (Piper nigrum) and cardamom (Elettaria cardamomum; ibid.).
Examples
of finds of opium poppies on British sites
The Early Iron Age Oakbank crannog (c. 820-500 BC) on Loch Tay in the Scottish Highlands (see: oakbank crannog) was originally constructed as a pile-dwelling that was occupied for c. 400 years (Miller et al. 1998). Excavations at the site revealed submerged layers with floor timbers covered in bracken and rushes and accumulations of household waste (e.g., similar to the Neolithic pile-dwellings described above) together with items for domestic use (e.g., wooden bowls, tools and other utensils). Preservation of waterlogged plant materials contained in the household waste was excellent and three opium poppy seeds were identified, possibly indicating local cultivation.
Papaver somniferum finds are frequently recorded on Roman sites. For example, in an organic layer (layer A) at the base of a perimeter ditch around Bearsden Roman fort (occupied from c. AD 140-160) on the Antonine Wall in Scotland, opium poppy remains were found together with fragments of wheat and barley grains, quantities of wheat pericarp and seeds and nuts of several edible wild species—both imported and local (e.g., figs (Ficus carica), coriander (Coriandrum sativum), wild celery (Apium graveolens), blackberries (Rubus fruticosus), raspberries (Rubus idaeus), strawberries (Fragaria vesca) , bilberries (Vaccinium myrtillus) and hazelnuts (Corylus avellana); Knights et al. 1983; see also: van der Veen et al. 2008). The authors suggested that the food remains were likely contained in sewage that had flowed into the ditch from adjacent bath house latrines, and their conclusion was supported by the fact that there were also eggs of intestinal parasites, fly puparia and maggots (the latter two indicative of rotting organic matter) in samples from layer A. (ibid.: 143; see also: Ancient Scotland -Bearsden Bathhouse). Papaver somniferum was also identified in 1st and 2nd century AD contexts at two sites in London (Willcox 1977).
Papaver somniferum seeds recovered from two medieval pits (one 15th century and the other late 16th/17th century) excavated in Sewer Lane in Hull are thought to be possible evidence for its cultivation in nearby gardens (Crackles 1986). Seeds and fruits of many economic taxa that would have been grown for domestic use were contained in the pit deposits, for example, herbs (e.g., pot marigold, Calendula officinalis; sweet cicely, Myrrhis odorata), vegetables (e.g., beet, Beta vulgaris; wild parsnip, Pastinaca sativa), spices (e.g., coriander, Coriandrum sativum) and medicinal plants (e.g., vervain, Verbena officinalis; purging flax, Linum cartharticum). And similarly, seeds of species found in 16th century deposits at sites in London provide information about plants that were common in early gardens within the city (Schofield 1999). Vegetables, herbs and spices (including opium poppy), cereals, fruits and nuts, and cucurbits (e.g., melon, Cucumis melo; watermelon, Citrillus lanatus; cucumber, Cucumis sativus) were all represented in the urban deposits (ibid.: table 1).
Textual and pictorial
evidence
The oldest text that describes the use of opium is dated to c. 2000 BC and is written on a cuneiform clay tablet found at the ancient Mesopotamian city of Nippur, in present day Iraq (Behn 1986; Stefano et al. 2017). The word ‘gil’, meaning joy, is mentioned in the inscribed text suggesting that the euphoric effects of opium as well as its medicinal properties were obviously well known to the Sumerians (see also: Did ancient Mesopotamians get high? Near Eastern ritualsmay have included opium, cannabis). A potion for sedating children that contains opium is depicted in hieroglyphs on the Ebers Papyrus (c. 1500 BC), a scroll about 100 pages long on which are recorded comprehensive details of Ancient Egyptian medicinal remedies (Hobbs 1998: 67).
Opium was a common ingredient
in remedies prescribed by Ancient Greek and Roman physicians (Megaloudi 2005; Scarborough
1978, 1998). Hippocrates (c. 460-370 BC; referred to as the ‘Father of
Medicine’) recommended the use of ‘meconium’
(e.g., poppy juice) as a purgative and narcotic (Astyrakaki et al. 2009; Stefano
et al. 2017). Aulus Cornelius Celsus (c. 25 BC – c. AD 50) who wrote ‘De Medicina’, a medical treatise
comprising six volumes about remedies, diet and surgical procedures, described
how to make pills using opium poppies mixed with wine (see General Anaesthesia– Aulus Cornelius Celsus).
In volume III he warned of the effects opium juice which, he noted, can induce a feeling of calm but should be taken with care because: “dreams can be sweet, but the sweeter they are, the rougher tends to be the awakening”. Pedanius Dioscorides (c. AD 40-90), a Greek surgeon who was in service in Nero’s army, wrote ‘De Materia Medica’, which was a comprehensive guide to plants and animals that could be used in various medicines and medical treatments, and it contained accounts of the beneficial effects of opium as an anaesthetic but also the dangers of its over-use: “taken as a drink too often it hurts (making men lethargic) and it kills” (De Materia Medica volume IV ‘Mekon Agrios and Mekon Emeros’ link to: Dioscorides). Pliny the Elder (AD 23/24-79) recommends the use of opium poppies to treat various ailments, including snakebites, and scorpion and spider stings (Scarborough 1978; see earlier references to ‘mithridatium’ and ‘theriac’). And it is thought that the physician and surgeon Aelius/Claudius Galenus ‘Galen’ (AD 129-200/216) was responsible for making opium generally acceptable to the people of Rome, although he too cautioned about its possible misuse (Stefano et al. 2017).
The portrayal of opium poppies in Roman frescoes is perhaps further indication of their importance in everyday use. A poppy plant is pictured in the garden scene on a wall in Livia’s Villa (dated to reign of Emperor Augustus, c. 30-20 BC) at Prima Porta in Rome (Caneva and Bohuny 2003). And an opium poppy pod features in a fresco in triclinium 14 in the Villa A (‘of Poppaea’) at Oplontis[x]—one of the Pompeian sites that was buried during the eruption of Vesuvius in AD 79. The pod is described as being large but that “[the] identification can be confirmed when we compare it with the large painting on the east wall of the diaeta in the House of the Golden Bracelet, and with the poppy pods in the mosaic of the House of the Faun” (Clarke and Muntassa c.2014; House of the Golden Bracelet; and House of the Faun).
The 12th century ‘Antidotorium Nicolai’—a medieval recipe book for making medicines from plants and minerals and referred to as ‘the essential pharmacopeia of the Middle Ages’[xi], lists the plant components of the ‘Great Rest’ or ‘Requies magna’, a remedy intended for sedating and/or reducing pain (Everett and Gabra 2014). In their study Everett and Gabra investigate the efficacy (and potential lethal dosages) of the ingredients of the ‘Great Rest’—including opium poppies; a translation of the instructions for its use that were originally written in Latin is as follows:
“Six parts are made from one pound. Take three drams (10.244g) each of roses and violets; one dram and a half (5.8 g) each of opium, henbane, meconium of white (opium) poppy, mandrake, wild lettuce, seeds of purslane, fleawort, nutmeg, cinnamon, and sugar. Two scruples and five grains (2.9 g) of white and red and citric sandalwood, ash, and tragacanth. Give with violet syrup to patients suffering acute fever; we can give it to them intermittently mixed with honey. It is given to those suffering quartan fevers with warm wine when the fever is acute or severe, and to these suffering tertian fever with warm water or syrup.” (Everett and Gabra 2014: 444, table 1).
The medieval Chilandar Medical Codex is a Serbian manuscript that comprises a compilation of texts on aspects of medical science (e.g., including instructions on how to make pills, ointments, balms and oils, etc.) dating from the 12th to the 15th centuries. (Jarić et al. 2011). Remedies made with plant, animal and inorganic ingredients are described in the manuscript and Papaver somniferum seeds are listed as being used to alleviate the effects of various health problems, for example, insomnia, hard swellings, chest pains and fevers (ibid.: table 1).
Laudanum and literature
“Collin’s later life – indeed, the entire second half of his life – was
overshadowed by a premature physical senescence. In the first instance this was
a matter of his contracting gout. As the attacks were regularly preluded by
periods of marked nervous depression, biographical science is inclined to
enlarge upon the psychosomatic character of his agonies. But agonies they were,
and he quickly came to find relief in laudanum. ….. Using it both as an anodyne
and mental stimulant, Collins came to take it not by so many drops but by the
glassful.”
(extract from J.I.M. Stewart’s
Introduction to the 1966 edition of The
Moonstone by Wilkie Collins)
Laudanum is a tincture of opium, made by dissolving c.10% of powdered opium in alcohol. It is an easily administered form of the drug and until the 20th century was still readily available and could be bought without a prescription. The 17th century physician Thomas Sydenham (1624-1689) is credited as being the first to use laudanum (e.g., in the form we know it today[xii]) to cure various illnesses, including epidemic diseases (Pearce 2016; Sigerist 1941; Thomas Sydenham info). However, about a hundred years earlier Paracelsus (full name: Philippus Aureolus Theophrastus Bombastus von Hohenheim, 1493/1494-1541), a German physician and alchemist, made a concoction he called laudanum but that differed from Sydenham’s because as well as opium it contained crushed pearls, gold leaf, musk and amber (an array of other ingredients are also listed by some authors; Sigerist 1941; Greek Medicine: Paraelsus)
Laudanum was considered to be a panacea for all ills and most households in the 19th century kept bottles of it for every-day use (Hayter 1980: see also Historic UK - Opium inVictorian Britain; Wellcome Collection – Drugs in Victorian Britain).
“A whole host of industrial workers in the North of England, both men
and women, took it weekly, as a cheaper escape from their miseries than either
beer or gin. Mothers and nurses gave it to fretful children. Writers, painters,
doctors, used it to tranquillize their nerves.”
(extract from Alethea Hayter’s Introduction to the 1971 edition of Confessions of an English opium eater by Thomas De Quincey)
Its influence on the works of many notable authors at that time is well known (Day and Smith 2002); laudanum heightened the imagination and enhanced creative expression, however, regular use inevitably lead to addiction. De Quincey (1785-1859) first took laudanum to alleviate the pain caused by neuralgia and gastric problems but he became ever more reliant on opium[xiii] to cope with the stresses of having to write to deadlines (e.g., for the London Magazine; Hayter 1982[1971]: 16); Hayter describes the consequence of bouts of indulgence in the drug:
“He found that by suddenly increasing his doses for a few days running, he enjoyed a glow of mental energy, ‘preter-natural paroxysms of intermitting power’ in which he could write brilliantly; but he paid for it by heavy suffering when the paroxysm was over.”
Wilkie Collins (1824-1889), who initially took laudanum for his painful gout, found that its continued use also adversely affected writing skills:
“Upon Collins himself the drug may have operated in a more subtly deleterious fashion, impairing his ability to produce that intricately plotted fiction which one would suppose especially to require a clear head.” (Stewart 1973[1966]: 19)
Other Victorian writers who used, and became addicted to laudanum included: Elizabeth [Mrs] Gaskell (1810-1865; author), Ada, Countess of Lovelace (1815-1852; mathematician, writer), Margaret [Mrs] Oliphant (1828-1897; author), Beatrice Webb (1858-1943; sociologist, economist, labour historian, social reformer), Samuel Taylor Coleridge (1772-1834, poet, literary critic, philosopher, theologian), Edgar Allan Poe (1809-1849; American author, poet, literary critic), and Percy Bysshe Shelley (1792-1822; poet; Hayter 1980; see also British Library – Representations of drugs in 19th century literature).
Bibliography
All Things Georgian. https://georgianera.wordpress.com/ [accessed: 02.07.20]
Allen, D.E. and Hatfield, G. 2004. Medicinal Plants in Folk Tradition: an Ethnobotany of Britain & Ireland. Timber Press, Portland/Cambridge.
Ancient Scotland. http://www.ancient-scotland.co.uk/ [accessed: 09.07.20]
Astyrakaki, E., Papaioannou, A. and Askitopoulou,H. 2009. References to anesthesia, pain and analgesia in the Hippocratic Collection. International Anesthesia Research Society 110(1): 188-194.
Askitopoulou, H., Ramoutsaki, I.A. and Konsolaki, E. 2002. Archaeological evidence on the use of opium in the Minoan World. International Congress Series. Volume 1242: 23-29.
Badura, M., Możejko, B., Święta-Musznicka, J. and Latałowa, M. 2015. The comparison of archaeobotanical data and the oldest documentary records (14th-15th century) of useful plants in medieval Gdańsk, northern Poland. Vegetation History and Archaeobotany 24: 441-454.
Bakels, C. 1982. Der Mohn, die Linearbandkeramik und das westliche Mittelmeergebiet. Archäologisches Korrespondenzblatt 12: 11-13.
Bakels, C. 2014. The first farmers of the Northwest European Plain: some remarks on their crops, crop cultivation and impact on the environment. Journal of Archaeological Science 51: 94-97.
Baudais, D., Grudler, A. and Lundstrom-Baudais, K. 1997. Les paléosemences du niveau VIII et leur répartition spatiale. In: P. Pétrequin, P. (ed.) Les sites littoraux néolithiques de Clairvaux-les-Lacs et de Chalain III (Jura). Paris, Editions de la Maison des Sciences de l'Homme pp.723-732.
Behn, C.P. 1986. The use of opium in the Bronze Age in the eastern Mediterranean. Listy filologické/Folia philologica 109(4); 193-197, I-III.
Bocquet, A., Caillat, R. and Lundstrom-Baudais, K. 1986. Alimentation et techniques de cuisson dans le village neolithique de Charavines — Isère Premiers documents. In: Demoule, J.-P. and Guilaine, J. (eds.). Le Néolithique de la France: homage à Gérard Bailloud. Paris: Picard.
Bollinger, T., 1994. Samenanalytische
Untersuchung der früh-jungsteinzeitlichen Seeufersiedlung Egozwil 3. Dissertationes Botanicæ 221. J. Cramer,
Berlin.
Brombacher, C. 1997 Archaeobotanical investigations of Late Neolithic lakeshore settlements (Lake Biel, Switzerland). Vegetation History and Archaeobotany 6: 167-186.
Brombacher, C. and Jacomet, S. 2003. Ackerbau, Sammelwirtschaft und Umwelt. In: Zwahlen, H. (ed.), Die jungneolithische Siedlung Port-Stüdeli, Volume 7 of Ufersiedlungen am Bielersee, pp. 66–86. Bern: Haupt.
Bunimovitz, S. and Lederman, Z. 2016. Opium or oil? Late Bronze Age Cypriot base ring juglets and international trade revisited. Antiquity 90: 1552-1561.
Canveva, G. and Bohuny, L. 2003. Botanic analysis of Livia’s villa painted flora (Prima Porta, Roma). Journal of Cultural Heritage 4: 149-155.
Ciaraldi, M. 2000. Drug preparation in evidence? An unusual plant and bone assemblage from the Pompeian countryside, Italy. Vegetation History and Archaeobotany 9: 91-98.
Clark, J.R. and Muntasser, N.K. c.2014. Oplontis: Villa A (‘of Poppaea’) at Torre Annunziata, Italy. ACLS Humanities E-Book https://quod.lib.umich.edu/cgi/t/text/text-idx?c=acls;cc=acls;rgn=div1;view=toc;idno=heb90048.0001.001;node=heb90048.0001.001:22 [accessed: 20.07.20]
Collins, W. 1973. The Moonstone. Reprint of 1966 edition. (first published in 1868) Penguin Books Ltd., Middlesex.
Crackles, F.E. 1986. Medieval gardens in Hull: archaeological evidence. Garden History 14(1): 1-5.
Cultural Evolution of Neolithic Europe. EUROEVOL https://www.ucl.ac.uk/euroevol/EUROEVOL/Home.html [accessed: 14.07.20]
Day, E. and Smith, I. 2002. Literary and biographical perspectives on substance use. Advances in Psychiatric Treatment 9: 62-68.
De Quincey, T. 1982. Confessions of an English opium eater. Reprint of 1971 edition. (first published in 1821) Penguin Books Ltd., Middlesex.
Dittbrenner, A., Mock, H.-P., Börner, U. and Lohwasser, U. 2009. Variability of alkaloid content in Papaver somniferum L. Journal of Applied Botany and Food Quality 82: 103-107.
Doğan, Y., Süleyman, B., Mert, H.H, and Güngör, Ay. 2003. Plants used as natural dye sources in Turkey. Economic Botany 57(4): 442-453.
Duke, J.A. 1973. Utilization of Papaver. Economic Botany 27(4): 390-400.
Everett, N. and Gabra, M. 2014. The pharmacology of medieval sedatives: the “Great Rest: of the Antidotorium Nicolai. Journal of Ethnopharmacology 155: 443-449.
Favre, P. 2002. Archaobotanik. In: Achour-Uster, C., Eberli, U., Ebersbach, R. and Favre, P. (eds.) Die Seeufersiedlungen in Horgen. Die neolithischen und bronzezeitlichen Fundstellen Dampfschiffsteg und Scheller. Fotorotar, Zurich, pp. 150–181.
Fontefrancesco, M., Barstow, C., Grazioli, F., Lyons, H., Mattalia, G., Marino, M., McKay, A.E., Sõukand, R., Corvo, P. and Pieroni, A. 2019. Keeping or changing? Two different cultural adaption strategies in the domestic use of home country food plant and herbal ingredients among Albanian and Moroccan migrants in Northwestern Italy. Journal of Ethnobiology and Ethnomedicine (2019) 15:11 https://doi.org/10.1186/s13002-019-0290-7
General Anaesthesia. https://www.general-anaesthesia.com/index.html [accessed: 17.07.20]
Gras, A., Serrasolses, G., Vallès, J. and Garnatje, T. 2019. Traditional knowledge in semi-rural close to industrial areas: ethnobotanical studies in western Gironès (Catalonia, Iberian Peninsula). Journal of Ethnobiology and Ethnomedicine (2019) 15:19 https://doi.org/10.1186/s13002-019-0295-2
Haber, I., Pergolizzi, J.Jnr. and LeQuang, J.A. 2019. Poppy seed tea: a short review and case study. Pain Therapy 8: 151-155.
Hayter, A. 1980. “The laudanum bottle loomed large”: opium in the English literary world in the nineteenth century. A Review of International English Literature 11(4): 37-51.
Hayter, A. 1982[1971].
Introduction. In: De Quincey, Confessions
of and English opium eater. Penguin Books Ltd., Middlesex. pp. 7-24.
Herbig, C. 2006 Archaeobotanical investigations in a settlement of the Horgener culture (3300 BC) 'Torwiesen II' at Lake Federsee, southern Germany. Environmental Archaeology 11(1): 131-142.
Historic UK. https://www.historic-uk.com/HistoryUK/ [accessed: 07.08.20]
Hobbs, J.T. 1998. The opium poppy in Egypt. Geographical Review 88(1): 64-85.
Jacomet, S., 1990. Veranderungen von Wirtschaft und Umwelt wahrend des Spat- neolithikums im westlichen Bodenseegebiet. Ergebnisse samenanalytischer Untersuchungen an einem Profilblock aus der Horgener Stratigraphie von Sipplingen-Osthafen. In: Billamboz, A., Czarnowski, E., Jacomet, S., Karg, S., Ostendorp, W., Rosch, M., Ruoff, U., Schlichtherle, H., Schmidt, E. and Suter, P. (eds.), Siedlungsarchaologie im Alpenvorland II. Forschungen und Berichte zur Vor- und Fruhgeschichte in Baden-Wurttemberg, 37, Stuttgart. pp. 295–324.
Jacomet, S., Leuzinger, U., Schibler, J., 2004. Die jungsteinzeitliche Seeufersiedlung Arbon Bleiche 3. In: Umwelt und Wirtschaft, Archäologie im Thurgau, vol. 12.
Jarić, S., Mitrović, M., Djurdjević, L., Kostić, O., Gajić, G., Pavlović, D. and Pavlović, P. 2011. Phytotherapy in medieval Serbian medicine according to the pharmacological manuscripts of the Chilandar Medical Codex (15-16th centuries). Journal of Ethnopharmacology 137: 601-619.
Knights, B.A., Dickson, C.A., Dickson, J.H. and Breeze, D.J. 1983. Evidence concerning the Roman military diet at Bearsden, Scotland, in the 2nd century AD. Journal of Archaeological Science 10:139-152.
Kroll, H. 1995. Literature on archaeological remains of cultivated plants (1992/1993). Vegetation History and Archaeobotany 4(1): 51-66
Kroll, H. 1996. Literature on archaeological remains of cultivated plants (1994/1995). Vegetation History and Archaeobotany 5(1-2): 169-200.
Kroll, H. 1997. Literature on archaeological remains of cultivated plants (1995/1996). Vegetation History and Archaeobotany 6(1): 25-67.
Kroll, H. 1998. Literature on archaeological remains of cultivated plants (1996/1997). Vegetation History and Archaeobotany 7(1): 23-56.
Kroll, H. 1999. Literature on archaeological remains of cultivated plants (1997/1998). Vegetation History and Archaeobotany 8(1-2): 129-163.
Kroll, H. 2000. Literature on archaeological remains of cultivated plants (1998/1999). Vegetation History and Archaeobotany 9(1): 31-68.
Kroll, H. 2001. Literature on archaeological remains of cultivated plants (1999/2000). Vegetation History and Archaeobotany 10: 33-60.
Kujawska, M., Klepacki, P. and Łuczaj, Ł. 2017. Fischer’s Plants in folk beliefs and customs: a previously unknown contribution to the ethnobotany of the Polish-Lithuanian-Belarusian borderland. Journal of Ethnobiology and Ethnomedicine (2017) 13:20 DOI 10.1186/s13002-017-0149-8
Kültür, Ş. 2007. Medicinal plants used in Kırklareli Province (Turkey). Journal of Ethnopharmacology 111: 341-364.
Łuczaj, Ł. 2011. Changes in Assumption Day herbal bouquets in Poland: a nineteenth century study. Economic Botany 65(1): 66-75.
Łuczaj, Ł., Köhler, P., Pirożnikow, E., Graniszewska, M., Pieroni, A. and Gervasi, T. 2013. Wild edible plants of Belarus: from Rostafiński’s questionnaire of 1883 to the present. Journal of Ethnobiology and Ethnomedicine 9:21 http://www.ethnobiomed.com/content/9/1/21
Lundström-Baudais, K. 1986. Étude paléoethnobotanique de la station III de Clairvaux. In: Petrequin, P. (ed.) Les Sites Littoraux Néolithiques de Clairvaux-Les-Lacs (Jura): I Problématique générale – L’example de la station III. Paris: Éditions de la Maison des Sciences de l’Homme. pp. 311-378.
Lundström-Baudais, K. 1989. Les macrorestes végétaux du niveau V de la Motte-aux-Magnins. In: Pétrequin, P. (ed.) Les sites littoraux néolithiques de Clairvaux-les-Lacs (Jura) – 2 – Le Néolithique moyen. pp. 417-439.
Maier, U. 2004. Archaöbotanische Untersuchungen in jung- und endneolithischen Moorseidlungen am Federsee. In: Köninger, J. and Schlichterle, H. (eds.) Ökonomischer und ökologischer Wandel am vorgeschichtlichen Federsee. Archäologische und naturwissenschaftliche Untersuchungen. Hemmnenhofener Skripte 5. Landesdenkmalamt Baden-Württemberg Archäologische Denkmalpflege. pp. 71-146.
Maier, U. and Harwath, A. 2011. Detecting intra-site patterns with systematic sampling strategies. Archaeobotanical grid sampling of lakeshore settlement Bad Bachau-Torwiesen II, southwest Germany. Vegetation History and Archaeobotany 20: 349-365.
Märkle, T. 2005. Nutrition, aspects of land use and environment in medieval times in southern Germany: plant macro-remain analyses from latrines (late 11th-13th century AD) at the town of Überlingen, Lake Constance. Vegetation History and Archaeobotany 14: 427-441.
Megaloudi, F. 2005. Wild and cultivated vegetables, herbs and spices in Greek Antiquity (900 BC to 400 BC). Environmental Archaeology 10: 73-82.
Merlin, M.D. 2003. Archaeological evidence for the tradition of psychoactive plant use in the Old World. Economic Botany 57(3): 295-323.
Merrillees, R.S. 1962. Opium trade in the Bronze Age Levant. Antiquity 36: 287-292.
Miller, J.J., Dickson, J.H. and Dixon, T.N. 19908. Unusual food plants from Oakbank Crannog, Loch Tay, Scottish Highlands: cloudberry, opium poppy and spelt wheat. Antiquity 72: 805-811.
Montesano, V., Negro, D., Sarli, G., De Lisi, A., Laghetti, G. and Hammer, K. 2012. Notes about the uses of plants by one of the last healers in the Basilicata region (South Italy). Journal of Ethnobiology and Ethnomedicine 8:15 http://www.ethnobiomed.com/content/8/1/15
National Biodiversity Database. https://nbnatlas.org [accessed: 03.06.20]
Neef, R. 1990. Botanische Untersuchungen im jungneolithischen Pestenacker. Die ersten Ergebnisse, Berichte der Römisch Germanischen Kommission (1990) 71: 381-389
NutritionValue.Org. https://www.nutritionvalue.org/ [accessed: 10.06.20]
Online
Atlas of the British and Irish Flora. Botanical Society of Britain &
Ireland. https://www.brc.ac.uk/plantatlas/ [accessed 03.06.20]
Riehl, S., 2004. Jungneolithische Pflanzenproduktion und Nutzung des Naturraums am Überlinger See/Bodensee: Archäobotanische Untersuchungen an Kulturschichtsedimenten aus der Seeufersiedlung Sipplingen. In: Köninger, J., Schlichtherle, H. (Eds.), Siedlungen der Pfyner Kultur im Osten der Pflahlbaubucht von Sipplingen, Bodenseekreis, Naturwissenschaftliche Untersuchungen. Hemmenhofener Skripte 4, Band 2, pp. 9-76.
Rivera, D., Verde, A.,
Fajardo, J., Obón, C., Consuegra, V., García-Botía, J., Ríos, S., Alcaraz, F.,
Valdés, A., del Moral, A. and Laguna, E. 2019. Ethnopharmacology in the Upper
Guadiana River area (Castile-La Mancha, Spain). Journal of Ethnopharmacology 241 (2019) 111968 https://doi.org/10.1016/j.jep.2019.111968
Scarborough, J. 1978. Theophrastus on herbals and herbal remedies. Journal of the History of Biology 11(2): 353-385.
Scarborough, J. 1998. Drugs and medicines in the Roman world. Expedition 38(2): 38-51.
Schofield, J. 1999. City of London gardens 1500 - c. 1620. Garden History 27(1): 73-88.
Schultz-Motel, J. 1994. Literature on archaeological remains of cultivated plants (1991/1992). Vegetation History and Archaeobotany 3: 33-61
ScienceMag.org [accessed: 15.07.20]
Sigerist, H.E. 1941. Laudanum in the works of Paracelsus. Bulletin of the History of Medicine 9: 530-544.
Simmonds, N.W. (ed.) 1976. Evolution of Crop Plants. Longman Group Ltd., USA NY.
Smith, R.K., Stacey, R.J., Bergström, E. and Thomas-Oates, J. 2018. Detection of opium alkaloids in a Cypriot base-ring juglet. Analyst 143: 5127-5137.
Stefano, G.B., Pilonis, N., Ptacek, R. and Kream, R.M. 2017. Reciprocal evolution of opiate science from medical and cultural perspectives. Medical Science Monitor 23: 2890-2896.
Stewart, J.I.M. 1973[1966]. Introduction. In: Collins, W., The Moonstone. Penguin Books Ltd., Middlesex. pp. 7-24.
Tagarelli, G., Tagarelli, A., Liguori, M. and Piro, A. 2013. Treating epilepsy in Italy between XIX and XX century. Journal of Ethnopharmacology 145: 608-613.
University of Virginia Historical Collections. http://exhibits.hsl.virginia.edu/treasures/ [accessed: 17.07.20]
US Drug Enforcement Administration. https://www.dea.gov/ [accessed: 08.07.20]
van der Veen, M., Livarda, A. and Hill, A. 2008. New plant foods in Roman Britain – dispersal and social access. Environmental Archaeology 13(1): 11-36.
Wellcome Collection. https://wellcomecollection.org/ [accessed: 07.08.20]
Willcox, G. 1977. Exotic plants from Roman waterlogged sites in London. Journal of Archaeological Science 4: 269-282.
Zibulski, P. 2010. Botanik. In: Eberli, U. (ed.), Die horgenzeitliche Siedlung Pfäffikon-Burg. Monographien der Kantonsarchäologie Zürich 40, Zürich und Egg. pp. 236-255.
Zohary, D., Hopf, M. and
Weiss, E. 2012. Domestication of Plants
in the Old World. 4th Edition. Oxford University Press, Oxford.
[i] The Encyclopædia Britannica describes alkaloids
as: “[classes] of naturally occurring
organic nitrogen-containing bases. Alkaloids have diverse and important
physiological effects on humans and other animals.” https://www.britannica.com/science/alkaloid [accessed: 09.06.20]
[ii] Malaria or other fever inducing illnesses.
[iii] See: Unesco World Heritage: Prehistoric Pile
Dwellings around the Alps. https://www.bodensee.eu/en/what-to-do/culture/unesco-world-heritage/pile-dwellings [accessed: 13.07.20]
[iv] Lists of Neolithic villages with large numbers
of waterlogged opium poppy remains:
Swiss sites: Egolzwil 3 (Bollinger 1994); Nidau-Schlossmatte (Brombacher 1997); Sutz-Lattrigen (Lattrigen
Hauptstation VII; Brombacher 1997); Arbon Bleiche 3 (Jacomet et al. 2004); Pfäffikon-Burg (Zibulski 2010); Port Stüdeli
(Brombacher and Jacomet 2003); Horgen-Scheller
(Favre 2002); Thayngen Weier (Robinson and Rasmussen 1989)
French sites: Motte-aux-Magnins (Lundström-Baudais 1989); Clairvaux Les Lacs station III (Lundström-Baudais 1986); Charavines ‘Les
Baigneurs’ (Bocquet et al. 1986); Chalaine 3 (Baudais et al. 1997)
German sites: Sipplingen (Riehl 2004);
Sipplingen-Osthafen (Jacomet 1990); Seekirch-Stockwiesen (Maier 2004); Alleshausen-Grundwiesen (Maier
2004); Seekirch-Achwiesen (Maier 2004); Pastenacker (Neef 1990); Torwiesen II
(Herbig 2006)
[v] The authors note that below the handle on jar
illustrated there is in relief the symbol of a snake, which is commonly
associated with healing and ritual in Bronze and Iron Age Greece.
[vi] See: Ancient Greece.org. https://ancient-greece.org/archaeology/mycenae.html [accessed: 10.07.20]
[vii] Mithridatium
was named after Mithridates VI, King of Pontus (135-63 BC), who made a potion
by combining different plant and animal ingredients as an antidote to
counteract the effects of poison. (N.B.: it is thought likely that the Greek
physician Crataeus may have helped Mithradites to concoct his remedy). http://penelope.uchicago.edu/~grout/encyclopaedia_Romana/aconite/mithridatum.htm [accessed:
18.06.20]
[viii] Theriac
is an improved version of Mithridatium,
with some ingredients substituted with others considered more efficacious, which
was made by Emperor Nero’s (AD 37-68) physician, Andromachus. https://wellcomecollection.org/articles/Wc5IPScAACgANNYO [accessed: 18.06.20]
[ix] Founded by the Teutonic Knights in 1350 and
one of the largest medieval grain mills in Europe.
https://medievalheritage.eu/en/main-page/heritage/poland/gdansk-medieval-mills/
[accessed: 14.07.20]
[x] See: Pompeii Sites.org. http://pompeiisites.org/en/oplontis/ [accessed: 14.07.20]
[xi] See: https://en.wikipedia.org/wiki/Antidotarium_Nicolai [accessed: 16.07.20]
[xii] Other recipes for laudanum are known (e.g., in
addition to those of Sydenham and Paracelsus) and as well as opium, ingredients
have included: saffron, cinnamon, cloves and sherry wine.
[xiii] Hayter notes in her introduction that: “De Quincey was an opium drinker, not an
opium eater; he generally took the drug in the form of laudanum”.
No comments:
Post a Comment